DISEASES

Disease-gene associations mined from literature

Literature associating HLA-DMA and distal arthrogryposis type 6

HLA-DMA [ENSP00000363976]

HLA class II histocompatibility antigen, DM alpha chain; Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Synonyms:  HLA-DMA,  RING6,  1HDM,  2BC4,  3108 ...

Linkouts:  STRING  Pharos