Disease-gene associations mined from literature

Literature associating TP53INP2 and estrogen-receptor negative breast cancer

TP53INP2 [ENSP00000363943]

Tumor protein p53 inducible nuclear protein 2; Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

Synonyms:  TP53INP2,  Q5JX65,  Q5JX66,  Q8IXH6,  TP53INP2-001 ...

Linkouts:  STRING  Pharos  UniProt