Literature associating HMGCL and methylmalonic acidemia
Hydroxymethylglutaryl-CoA lyase, mitochondrial; Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
Synonyms: HMGCL, B1AK13, D6REN8, P35914, B1AK13p ...