DISEASES

Disease-gene associations mined from literature

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Literature associating PTPN20A and Noonan syndrome with multiple lentigines 1

PTPN20A [ENSP00000363459]

Protein tyrosine phosphatase, non-receptor type 20A; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.

Synonyms:  PTPN20A,  LOC102725179,  PTPN20Ap,  hPTPN20A,  PTPN20B ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.