Literature associating INIP and Kabuki syndrome
Single-stranded DNA-binding protein-interacting protein 1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single- stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Synonyms: INIP, Q5VWJ6, Q9NRY2, X6R8P6, C9orf80 ...