Literature associating TRAF3IP1 and asphyxiating thoracic dystrophy 3
TNF receptor-associated factor 3 interacting protein 1; Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity); Intraflagellar transport proteins
Synonyms: TRAF3IP1, H7BZ10, Q8TDR0, H7BZ10p, hH7BZ10 ...