Literature associating ADPRHL2 and autosomal recessive hypercholesterolemia
[Protein ADP-ribosylarginine] hydrolase-like protein 2; Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.
Synonyms: ADPRHL2, ADPRHL2p, hADPRHL2, B4DHV5, B7ZAN4 ...