DISEASES

Disease-gene associations mined from literature

Literature associating TREM2 and frontotemporal dementia

TREM2 [ENSP00000362205]

Triggering receptor expressed on myeloid cells 2; Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines; V-set domain containing

Synonyms:  TREM2,  TREM2p,  hTREM2,  E3WHI5,  Q5TCX1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM