DISEASES

Disease-gene associations mined from literature

Literature associating FRS3 and multiple endocrine neoplasia type 4

FRS3 [ENSP00000362109]

Fibroblast growth factor receptor substrate 3; Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.

Synonyms:  FRS3,  FRS3p,  hFRS3,  A6PVU0,  O43559 ...

Linkouts:  STRING  Pharos  UniProt