Disease-gene associations mined from literature

Literature associating NOX1 and autosomal recessive chronic granulomatous disease cytochrome b-negative

NOX1 [ENSP00000362057]

NADH/NADPH mitogenic oxidase subunit P65-MOX; NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.

Synonyms:  NOX1,  NOX1p,  hNOX1,  A6NGA6,  NOX1-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM