Literature associating CTPS1 and immunodeficiency 24
UTP--ammonia ligase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP- dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity; Glutamine amidotransferase like class 1 domain containing
Synonyms: CTPS1, CTPS1p, hCTPS1, B4DR64, B4E1E0 ...