Disease-gene associations mined from literature

Literature associating ESX1 and pituitary gland disease

ESX1 [ENSP00000361669]

Extraembryonic, spermatogenesis, homeobox 1; May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover; PRD class homeoboxes and pseudogenes

Synonyms:  ESX1,  ESX1p,  hESX1,  A6ZIT2,  A6ZIU4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM