Literature associating ESX1 and pituitary gland disease
Extraembryonic, spermatogenesis, homeobox 1; May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover; PRD class homeoboxes and pseudogenes
Synonyms: ESX1, ESX1p, hESX1, A6ZIT2, A6ZIU4 ...