Disease-gene associations mined from literature

Literature associating MMP9 and arteriosclerosis

MMP9 [ENSP00000361405]

67 kDa matrix metalloproteinase-9; May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. ; Belongs to the peptidase M10A family.

Synonyms:  MMP9,  MMP9p,  hMMP9,  P14780,  P14780p ...

Linkouts:  STRING  Pharos  UniProt  OMIM