DISEASES

Disease-gene associations mined from literature

Literature associating MMP9 and carotid stenosis

MMP9 [ENSP00000361405]

Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide; M10 matrix metallopeptidases

Synonyms:  MMP9,  MMP9p,  hMMP9,  MMP9-001,  P14780 ...

Linkouts:  STRING  Pharos  UniProt  OMIM