DISEASES

Disease-gene associations mined from literature

Literature associating AMOT and transient myeloproliferative syndrome

AMOT [ENSP00000361027]

Angiomotin; Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions; Belongs to the angiomotin family.

Synonyms:  AMOT,  A2BDD9,  A6NP16,  E7ERM3,  Q4VCS5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM