Literature associating AGBL4 and congenital mesoblastic nephroma
ATP/GTP binding protein-like 4; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS/MB21D1, regulating the antiviral activity of CGAS/MB21D1. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5; M14 carboxypeptidases
Synonyms: AGBL4, AGBL4p, hAGBL4, A0AVJ2, B1AMW3 ...