DISEASES

Disease-gene associations mined from literature

Literature associating KCNT1 and West syndrome

KCNT1 [ENSP00000360822]

Potassium channel, subfamily T, member 1; Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity); Belongs to the potassium channel family. Calcium- activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.

Synonyms:  KCNT1,  KCNT1p,  hKCNT1,  C9J9Y7,  C9JAX7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM