Disease-gene associations mined from literature

Literature associating HOOK1 and spermatogenic failure 16

HOOK1 [ENSP00000360252]

Hook microtubule-tethering protein 1; Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).

Synonyms:  HOOK1,  HOOK1p,  hHOOK1,  A8MU44,  B1AK95 ...

Linkouts:  STRING  Pharos  UniProt  OMIM