Literature associating HOOK1 and spermatogenic failure 16
Hook microtubule-tethering protein 1; Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
Synonyms: HOOK1, HOOK1p, hHOOK1, A8MU44, B1AK95 ...