Disease-gene associations mined from literature

Literature associating FOXD3 and branchiooculofacial syndrome

FOXD3 [ENSP00000360157]

HNF3/FH transcription factor genesis; Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis; Forkhead boxes

Synonyms:  FOXD3,  FOXD3p,  hFOXD3,  Q9UJU5,  Genesis ...

Linkouts:  STRING  Pharos  UniProt  OMIM