Disease-gene associations mined from literature

Literature associating GNAS and obesity

GNAS [ENSP00000360141]

Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity).

Synonyms:  GNAS,  A0A0A0MR13,  A0A0S2Z3H8,  A0A0S2Z3S5,  A2A2R6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM