Disease-gene associations mined from literature

Literature associating BCL10 and pancreatic acinar cell adenocarcinoma

BCL10 [ENSP00000359612]

CED-3/ICH-1 prodomain homologous E10-like regulator; Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF- kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Synonyms:  BCL10,  BCL10p,  hBCL10,  O95999,  CIPER ...

Linkouts:  STRING  Pharos  UniProt