Literature associating BCL10 and T-cell acute lymphoblastic leukemia
CED-3/ICH-1 prodomain homologous E10-like regulator; Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF- kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
Synonyms: BCL10, BCL10p, hBCL10, O95999, CIPER ...