DISEASES

Disease-gene associations mined from literature

Literature associating PTBP2 and spinal cord glioma

PTBP2 [ENSP00000359216]

Neural polypyrimidine tract-binding protein; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

Synonyms:  PTBP2,  PTBP2p,  hPTBP2,  B4DSI2,  O95652 ...

Linkouts:  STRING  Pharos  UniProt