DISEASES

Disease-gene associations mined from literature

Literature associating FBXW4 and split hand-foot malformation

FBXW4 [ENSP00000359149]

F-box and WD-40 domain-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling; F-box and WD repeat domain containing

Synonyms:  FBXW4,  FBXW4p,  hFBXW4,  FBXW4-001,  FBXW4-002 ...

Linkouts:  STRING  Pharos  UniProt