Literature associating CYP17A1 and adrenocortical carcinoma
Cytochrome P450, family 17, subfamily A, polypeptide 1; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty; Belongs to the cytochrome P450 family.
Synonyms: CYP17A1, CYP17A1p, hCYP17A1, C7F7K7, P05093 ...