Literature associating TTK and hereditary mixed polyposis syndrome
Phosphotyrosine picked threonine-protein kinase; Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Synonyms: TTK, D6REX1, D6RF82, D6RFY1, D6RIC6 ...