Literature associating CYB5R4 and methemoglobinemia
N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.
Synonyms: CYB5R4, CYB5R4p, hCYB5R4, B2R7W7, CYB5R4-001 ...