DISEASES

Disease-gene associations mined from literature

Literature associating SYCP1 and testicular cancer

SYCP1 [ENSP00000358535]

Synaptonemal complex protein 1; Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.

Synonyms:  SYCP1,  SYCP1p,  hSYCP1,  A0A024R0I2,  Q15431 ...

Linkouts:  STRING  Pharos  UniProt