DISEASES

Disease-gene associations mined from literature

Literature associating CD58 and hemoglobinuria

CD58 [ENSP00000358501]

Lymphocyte function-associated antigen 3; Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Synonyms:  CD58,  CD58p,  hCD58,  B1AMW1,  H0YDI1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM