DISEASES

Disease-gene associations mined from literature

Literature associating SHOC2 and cryptorchidism

SHOC2 [ENSP00000358464]

Soc-2 suppressor of clear homolog (C. elegans); Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

Synonyms:  SHOC2,  SHOC2p,  hSHOC2,  Q9UQ13,  SHOC2-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM