Disease-gene associations mined from literature

Literature associating ADRB1 and systolic heart failure

ADRB1 [ENSP00000358301]

Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.

Synonyms:  ADRB1,  ADRB1p,  hADRB1,  ADRB1-001,  P08588 ...

Linkouts:  STRING  Pharos  UniProt  OMIM