DISEASES

Disease-gene associations mined from literature

SearchDownloadsAbout

Literature associating SIM1 and Down syndrome

SIM1 [ENSP00000358210]

Single-minded family bHLH transcription factor 1; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult; Basic helix-loop-helix proteins

Synonyms:  SIM1,  SIM1p,  hSIM1,  P81133,  BHLHE14 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.