Literature associating HIST2H2BE and familial hyperinsulinemic hypoglycemia 1
HIST2H2BE [ENSP00000358151]
Histone cluster 2, H2be; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: HIST2H2BE, Q16778, Q8N257, H2BFQ, HIST3H2BB ...