Literature associating H2BC21 and familial hyperinsulinemic hypoglycemia 1
H2BC21 [ENSP00000358151]
Histone H2B type 2-E; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: H2BC21, H2BC21p, hH2BC21, HIST2H2BE, Q16778 ...