DISEASES

Disease-gene associations mined from literature

Literature associating MCL1 and acute lymphocytic leukemia

MCL1 [ENSP00000358022]

Induced myeloid leukemia cell differentiation protein Mcl-1; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis; Belongs to the Bcl-2 family.

Synonyms:  MCL1,  MCL1p,  hMCL1,  B4DG83,  Q07820 ...

Linkouts:  STRING  Pharos  UniProt  OMIM