DISEASES

Disease-gene associations mined from literature

Literature associating LACE1 and marasmus

LACE1 [ENSP00000357973]

Lactation elevated protein 1; Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.

Synonyms:  LACE1,  LACE1p,  hLACE1,  A6ZJA2,  AFG1L ...

Linkouts:  STRING  Pharos  UniProt