Disease-gene associations mined from literature

Literature associating UROS and inflammatory and toxic neuropathy

UROS [ENSP00000357787]

Hydroxymethylbilane hydrolyase [cyclizing]; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).

Synonyms:  UROS,  P10746,  Q5T3L7,  Q5T3L8,  Q5T3L9 ...

Linkouts:  STRING  Pharos  UniProt