Disease-gene associations mined from literature

Literature associating NKX6-2 and spastic ataxia 8

NKX6-2 [ENSP00000357581]

Homeobox protein NK-6 homolog B; Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'- (A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions; NKL subclass homeoboxes and pseudogenes

Synonyms:  NKX6-2,  Q9C056,  GTX,  NKX6B,  Q9C056p ...

Linkouts:  STRING  Pharos  UniProt