Literature associating NKX6-2 and hypomyelinating leukodystrophy
Homeobox protein NK-6 homolog B; Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'- (A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions; NKL subclass homeoboxes and pseudogenes
Synonyms: NKX6-2, Q9C056, GTX, NKX6B, Q9C056p ...