Literature associating HEY2 and hypoplastic left heart syndrome
Hes-related family bHLH transcription factor with YRPW motif 2; Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6; Belongs to the HEY family.
Synonyms: HEY2, HEY2p, hHEY2, B4E1L3, Q5TF93 ...