DISEASES

Disease-gene associations mined from literature

Literature associating NR1I3 and intrahepatic cholestasis of pregnancy

NR1I3 [ENSP00000356959]

Nuclear receptor subfamily 1, group I, member 3; Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element; Belongs to the nuclear hormone receptor family. NR1 subfamily.

Synonyms:  NR1I3,  NR1I3p,  hNR1I3,  B7Z8R7,  C0H5Y2 ...

Linkouts:  STRING  Pharos  UniProt