DISEASES

Disease-gene associations mined from literature

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Literature associating IFNGR1 and eczema herpeticum

IFNGR1 [ENSP00000356713]

Interferon gamma receptor alpha-chain; Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway; CD molecules

Synonyms:  IFNGR1,  IFNGR1p,  hIFNGR1,  A1Z2M9,  B4DFT7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.