Disease-gene associations mined from literature

Literature associating SERPINC1 and alpha-2-plasmin inhibitor deficiency

SERPINC1 [ENSP00000356671]

Serpin peptidase inhibitor, clade C (antithrombin), member 1; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin; Serpin peptidase inhibitors

Synonyms:  SERPINC1,  A0A024R944,  AT3,  P01008,  Q8J001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM