Literature associating TAB2 and type 1 diabetes mellitus 5
Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'- linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development; Zinc fingers RANBP2-type
Synonyms: TAB2, TAB2p, hTAB2, Q9NYJ8, TAB2-001 ...