DISEASES

Disease-gene associations mined from literature

Literature associating FHR2 and macular degeneration

FHR2 [ENSP00000356385]

Complement factor H-related 2; Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.

Synonyms:  CFHR2,  CFHR2p,  hCFHR2,  CFHR2-001,  CFHR2-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM