Disease-gene associations mined from literature

Literature associating PCMT1 and type 1 diabetes mellitus 5

PCMT1 [ENSP00000356354]

protein-L-isoaspartate (D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine- binding protein 1, stathmin, beta-synuclein and alpha-synuclein; Seven-beta-strand methyltransferase motif containing

Synonyms:  PCMT1,  PCMT1p,  hPCMT1,  B7Z972,  C9J0F2 ...

Linkouts:  STRING  Pharos  UniProt