Literature associating MDM4 and hydranencephaly
Mdm2-like p53-binding protein; Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions; Ring finger proteins
Synonyms: MDM4, MDM4p, hMDM4, A0A024R990, DKFZP686B01123 ...