DISEASES

Disease-gene associations mined from literature

Literature associating NUAK2 and omphalocele

NUAK2 [ENSP00000356125]

NUAK family, SNF1-like kinase, 2; Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.

Synonyms:  NUAK2,  NUAK2p,  hNUAK2,  B4E0Y5,  DKFZP686F01113 ...

Linkouts:  STRING  Pharos  UniProt  OMIM