DISEASES

Disease-gene associations mined from literature

Literature associating IRF2BP2 and acute promyelocytic leukemia

IRF2BP2 [ENSP00000355568]

Interferon regulatory factor 2 binding protein 2; Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle; Belongs to the IRF2BP family.

Synonyms:  IRF2BP2,  IRF2BP2p,  hIRF2BP2,  B4DTU9,  Q7Z5L9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM