Disease-gene associations mined from literature

Literature associating RGS7 and congenital stationary night blindness

RGS7 [ENSP00000355523]

Regulator of G-protein signaling 7; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.

Synonyms:  RGS7,  RGS7p,  hRGS7,  B7Z223,  B7Z257 ...

Linkouts:  STRING  Pharos  UniProt  OMIM