Literature associating GRM1 and autosomal dominant hypocalcemia
Glutamate receptor, metabotropic 1; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Synonyms: GRM1, GRM1p, hGRM1, Q13255, GPRC1A ...